Abstract | BACKGROUND: This study defines the entity of the hypertensive lower esophageal sphincter (HLES) and its treatment, including surgical implications. METHODS: Esophageal manometry was performed on 1,300 patients. Of these, 53 (4%) had HLES with resting pressure > 26.5 mm Hg, defined as the upper limit of normal resting LES pressure. Thirty-two of these patients had 24-hour esophageal pH studies. The response to treatment was assessed. RESULTS: CONCLUSIONS: Patients with the HLES form a heterogeneous group. Gastroesophageal reflux in HLES patients is not uncommon. Patients with HLES respond well to medical therapy. Carefully selected patients require surgery.
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Authors | N Katada, R A Hinder, P R Hinder, R J Lund, G Perdikis, R A Stalzer, T R McGinn |
Journal | American journal of surgery
(Am J Surg)
Vol. 172
Issue 5
Pg. 439-42; discussion 442-3
(Nov 1996)
ISSN: 0002-9610 [Print] United States |
PMID | 8942540
(Publication Type: Clinical Trial, Journal Article)
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Topics |
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Esophageal Motility Disorders
(etiology, physiopathology, surgery)
- Esophagogastric Junction
(physiopathology)
- Female
- Follow-Up Studies
- Humans
- Hypertension
(complications, physiopathology)
- Male
- Manometry
- Middle Aged
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