Leucocytoclastic vasculitis in a patient with azathioprine hypersensitivity.

Abstract

We report the case of a 77-year-old man admitted nine days after being commenced on azathioprine with symptoms initially thought to be secondary to sepsis but in fact due to azathioprine hypersensitivity. He developed histologically proven cutaneous leucocytoclastic vasculitis following the re-introduction of azathioprine. We review the literature concerning adverse reactions to azathioprine and the problems of making the diagnosis as well as highlighting azathioprine as a novel cause of leucocytoclastic vasculitis.

• Authors: C G Beckett, P Hill, K R Hine
• Journal: Postgraduate medical journal (Postgrad Med J) Vol. 72 Issue 849 Pg. 437-8 (Jul 1996) ISSN: 0032-5473 [Print] England
• PMID: 8935609 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Immunosuppressive Agents
• Azathioprine

Topics

• Aged
• Azathioprine (adverse effects)
• Humans
• Immunosuppressive Agents (adverse effects, therapeutic use)
• Male
• Vasculitis, Leukocytoclastic, Cutaneous (chemically induced, diagnosis)