HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Intravenous arginine dramatically improved hyperammonemia in a patient with late-onset ornithine transcarbamylase deficiency.

Abstract
We describe a 12 year-old male patient with late-onset ornithine transcarbamylase deficiency, in whom infusion of arginine alone dramatically improved intercurrent hyperammonemia. The plasma glutamine level also decreased while the urea nitrogen level increased with arginine infusion, indicating that accumulated nitrogen was metabolized to urea in response to the arginine infusion.
AuthorsH Kodama, Y Mori, K Kubota, T Iitsuka, Y Nakazato, T Abe
JournalThe Tohoku journal of experimental medicine (Tohoku J Exp Med) Vol. 180 Issue 1 Pg. 83-6 (Sep 1996) ISSN: 0040-8727 [Print] Japan
PMID8933675 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Ammonia
  • Arginine
  • Ornithine Decarboxylase
Topics
  • Ammonia (blood)
  • Arginine (blood, therapeutic use)
  • Child
  • Humans
  • Injections, Intravenous
  • Liver (enzymology)
  • Male
  • Ornithine Decarboxylase (deficiency, metabolism)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: