HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

The effects of a mouthrinse containing sodium benzoate and alcohol on the quantity and metabolism of dental plaque.

Abstract
The aim of this study was to investigate the efficacy of a pre-brushing rinse containing sodium benzoate and alcohol, on 2 week old dental plaque. In a double-blind, placebo-controlled crossover study 20 individuals abstained from oral hygiene for periods of 2 weeks. Ten individuals were then assigned to rinse once for 30 seconds with either the test mouthrinse or a placebo mouthrinse. Following this, all individuals had their teeth cleaned and maintained proper oral hygiene for four weeks before the experiment was repeated. This time, the control individuals were assigned to the test rinse and vice versa. Using the Plaque Index on three buccal sites on all teeth, plaque was recorded before and after rinsing, as well as following a subsequent toothbrushing. For metabolic studies plaque from the lingual surfaces on the teeth in one quadrant in the upper and the lower jaw was sampled before rinsing and from the two remaining quadrants following the rinse, and analysed. There was no difference in Plaque Index between the two experimental periods. An oral rinse with the test mouthrinse had no effect on the amount of plaque, nor did it enhance the subsequent plaque removal after brushing. The independent biochemical analysis showed a significant effect of rinsing on the glycolytic potential, but with no effect on the glycolytic profile, which was similar for test and control plaque samples. Thus, a single oral rinse with a mouthrinse containing sodium benzoate and alcohol does not affect removal of plaque nor does it seems to influence the glycolytic potential of the plaque.
AuthorsB Danielsen, O Fejerskov, A A Scheie
JournalInternational dental journal (Int Dent J) Vol. 46 Issue 2 Pg. 91-6 (Apr 1996) ISSN: 0020-6539 [Print] England
PMID8930680 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
Chemical References
  • Acids
  • Benzoates
  • Mouthwashes
  • Placebos
  • Ethanol
  • Benzoic Acid
  • Glucose
Topics
  • Acids (metabolism)
  • Adult
  • Benzoates (administration & dosage, therapeutic use)
  • Benzoic Acid
  • Cross-Over Studies
  • Dental Plaque (metabolism, pathology)
  • Dental Plaque Index
  • Dental Prophylaxis
  • Double-Blind Method
  • Ethanol (administration & dosage, therapeutic use)
  • Glucose (metabolism)
  • Glycolysis
  • Humans
  • Mouthwashes (therapeutic use)
  • Oral Hygiene
  • Placebos
  • Toothbrushing

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: