Successful treatment of molluscum contagiosum in the immunosuppressed adult with topical injection of streptococcal preparation OK-432.

Abstract

A 37-year-old Japanese woman received an anticancer drug for 5 years following resection of mammary cancer and then developed widespread mollusca contagiosa, which we considered to be caused by immunosuppression induced by the chemotherapy. Because OK-432 (penicillin-treated and heat-treated lyophilized powder by a substrain of Streptococcus pyogenes A) was expected to be effective for immunosuppression, we tried its topical injection. The skin lesions disappeared almost completely within three months. OK-432 therapy is considered hopeful for treating viral skin diseases, even in immunosuppressed patients.

• Authors: S Inui, H Asada, K Yoshikawa
• Journal: The Journal of dermatology (J Dermatol) Vol. 23 Issue 9 Pg. 628-30 (Sep 1996) ISSN: 0385-2407 [Print] England
• PMID: 8916664 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Antineoplastic Agents
• Picibanil

Topics

• Adult
• Antineoplastic Agents (administration & dosage, adverse effects, therapeutic use)
• Breast Neoplasms (complications, immunology)
• Female
• Humans
• Immunocompromised Host
• Injections, Intradermal
• Molluscum Contagiosum (complications, drug therapy)
• Picibanil (administration & dosage, therapeutic use)