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Thoracic spinal Pantopaque cyst and associated syrinx resulting in progressive spastic paraparesis: case report.

AbstractOBJECTIVE AND IMPORTANCE:
We describe a unique presentation of a thoracic spinal Pantopaque cyst. Although Pantopaque is no longer used, sequelae of its long-term use may continue to surface.
CLINICAL PRESENTATION:
Our patient presented to the emergency room with 4 months of progressive lower extremity numbness, spasticity, and incontinence and a 2-day history of left upper extremity dysesthesias. Magnetic resonance imaging at admission revealed a C7-T10 syrinx and an intrathecal extramedullary mass to the right of the spinal cord at T10-T11.
INTERVENTION:
Radiographic evidence led to the initial diagnosis of hemangioblastoma. The results of a critical analysis of the preoperative studies caused us to suspect a Pantopaque cyst. This suspicion was confirmed at the time of surgery, when a cyst filled with contrast medium was revealed. T9-T11 laminectomies were performed, allowing for a 5-cm dural opening. The cyst was aspirated and excised, and then the syrinx was decompressed.
CONCLUSION:
Our patient experienced significant sensory and motor improvement postoperatively. We present a previously undescribed complication of one of the most commonly used contrast media, Pantopaque. Despite its replacement with newer agents, it may continue to play a significant role in the pathological presentation of patients in whom it was previously used.
AuthorsE N Tabor, U Batzdorf
JournalNeurosurgery (Neurosurgery) Vol. 39 Issue 5 Pg. 1040-2 (Nov 1996) ISSN: 0148-396X [Print] United States
PMID8905763 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Contrast Media
  • Iophendylate
Topics
  • Adult
  • Angiography
  • Contrast Media (adverse effects)
  • Cysts (chemically induced, diagnosis, surgery)
  • Humans
  • Iophendylate (adverse effects)
  • Magnetic Resonance Imaging
  • Male
  • Paraparesis, Tropical Spastic (chemically induced, diagnosis, surgery)
  • Spinal Diseases (chemically induced, diagnosis, surgery)
  • Syringomyelia (chemically induced, diagnosis, surgery)
  • Thorax

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