Abstract |
Tinidazole, a recent derivative of the nitroimidazole group of compounds, was able to achieve a cure in 96% of children with acute amebic dysentery when given in three single daily doses of approximately 60 mg/kg of body weight. At a dose of approximately 50 mg/kg the cure rate was only 76%. The drug was well tolerated and completely free from any toxic effects. Tinidazole can confidently be recommended as a very simple and safe form of therapy for amebic dysentery.
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Authors | J N Scragg, E M Proctor |
Journal | The American journal of tropical medicine and hygiene
(Am J Trop Med Hyg)
Vol. 26
Issue 4
Pg. 824-5
(Jul 1977)
ISSN: 0002-9637 [Print] United States |
PMID | 889024
(Publication Type: Journal Article)
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Chemical References |
- Nitroimidazoles
- Tinidazole
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Topics |
- Acute Disease
- Child
- Child, Preschool
- Dysentery, Amebic
(drug therapy)
- Humans
- Infant
- Nitroimidazoles
(therapeutic use)
- Tinidazole
(administration & dosage, therapeutic use)
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