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Tinidazole treatment of acute amebic dysentery in children.

Abstract
Tinidazole, a recent derivative of the nitroimidazole group of compounds, was able to achieve a cure in 96% of children with acute amebic dysentery when given in three single daily doses of approximately 60 mg/kg of body weight. At a dose of approximately 50 mg/kg the cure rate was only 76%. The drug was well tolerated and completely free from any toxic effects. Tinidazole can confidently be recommended as a very simple and safe form of therapy for amebic dysentery.
AuthorsJ N Scragg, E M Proctor
JournalThe American journal of tropical medicine and hygiene (Am J Trop Med Hyg) Vol. 26 Issue 4 Pg. 824-5 (Jul 1977) ISSN: 0002-9637 [Print] United States
PMID889024 (Publication Type: Journal Article)
Chemical References
  • Nitroimidazoles
  • Tinidazole
Topics
  • Acute Disease
  • Child
  • Child, Preschool
  • Dysentery, Amebic (drug therapy)
  • Humans
  • Infant
  • Nitroimidazoles (therapeutic use)
  • Tinidazole (administration & dosage, therapeutic use)

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