Acinic cell-like carcinoma of the breast.

Abstract

A case of infiltrating carcinoma of the breast with features similar to those seen in acinic cell carcinoma of the parotid gland is described in a 42-year-old woman. The neoplastic cells were immunoreactive with anti-lysozyme- and anti-salivary-type amylase antisera and contained electron-dense cytoplasmic globules similar to those seen in acinic cell carcinoma of salivary glands. One lymph node out of 18 was found to contain a metastatic deposit. The patient is alive and well 1 year after mastectomy. This appears to be the first case of carcinoma with acinic cell-like features reported in the breast.

• Authors: F Roncaroli, J Lamovec, A Zidar, V Eusebi
• Journal: Virchows Archiv : an international journal of pathology (Virchows Arch) Vol. 429 Issue 1 Pg. 69-74 (Sep 1996) ISSN: 0945-6317 [Print] Germany
• PMID: 8865856 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Immune Sera
• Amylases
• Muramidase

Topics

• Adult
• Amylases (analysis, immunology)
• Breast Neoplasms (chemistry, pathology, ultrastructure)
• Carcinoma, Acinar Cell (chemistry, pathology, ultrastructure)
• Female
• Humans
• Immune Sera (analysis, immunology)
• Immunohistochemistry
• Lymph Nodes (pathology)
• Microscopy, Electron
• Muramidase (analysis, immunology)
• Parotid Neoplasms (chemistry, pathology, ultrastructure)