Association between HLA antigens and early onset periodontitis.

Abstract

HLA-A, B, C and DR antigen frequencies were determined in a group of patients with juvenile periodontitis and rapidly progressive periodontitis. In juvenile periodontitis patients, HLA-A24 and DR4 were found at a significantly higher level than in the control group, and in rapidly progressive periodontitis patients, A9 and DR4 were found at a significantly higher level than the control group. The presence of these antigens gives evidence as to the susceptibility of various forms of early onset periodontitis.

• Authors: E Firatli, A Kantarci, I Cebeci, H Tanyeri, G Sönmez, M Carin, O Tuncer
• Journal: Journal of clinical periodontology (J Clin Periodontol) Vol. 23 Issue 6 Pg. 563-6 (Jun 1996) ISSN: 0303-6979 [Print] United States
• PMID: 8811476 (Publication Type: Journal Article)

Chemical References

• HLA Antigens
• HLA-A Antigens
• HLA-A24 Antigen
• HLA-A9 antigen
• HLA-B Antigens
• HLA-C Antigens
• HLA-DR Antigens
• HLA-DR4 Antigen

Topics

• Adolescent
• Adult
• Aggressive Periodontitis (immunology)
• Disease Susceptibility (immunology)
• Female
• HLA Antigens (analysis)
• HLA-A Antigens (analysis)
• HLA-A24 Antigen
• HLA-B Antigens (analysis)
• HLA-C Antigens (analysis)
• HLA-DR Antigens (analysis)
• HLA-DR4 Antigen (analysis)
• Humans
• Male
• Periodontitis (immunology)