Utility of technetium-99m-sestamibi to assess osseous tumor spread.

Abstract

We report the staging results and the surgical outcome of a male patient with squamous-cell carcinoma in the floor of the mouth and a bone SPECT scan suggestive of local tumor infiltration of the mandible. Additional 99mTc-sestamibi SPECT imaging of the primary tumor and superimposing of both studies excluded osseous tumor spread and less extensive surgery was performed. Pathohistological examination confirmed the scintigraphic results and indicated a nonspecific periostal reaction as the cause of the positive bone scan. Nevertheless, a high-resolution camera and careful superimposition of both studies is mandatory if the differential diagnosis of an osseous tumor spread of a malignant tumor in the floor of the mouth and possibly less extensive surgery is at stake.

• Authors: C Glaser, M Pruckmayer, A Staudenherz, M Rasse, S Lang, T Leitha
• Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine (J Nucl Med) Vol. 37 Issue 9 Pg. 1526-8 (Sep 1996) ISSN: 0161-5505 [Print] United States
• PMID: 8790209 (Publication Type: Case Reports, Journal Article)

Chemical References

• Diphosphonates
• Organotechnetium Compounds
• technetium Tc 99m 1,1-diphosphonopropane-2,3-dicarboxylic acid
• Technetium Tc 99m Sestamibi

Topics

• Carcinoma, Squamous Cell (diagnostic imaging, pathology)
• Diphosphonates
• Humans
• Male
• Mandibular Neoplasms (diagnostic imaging, pathology)
• Mouth Floor
• Mouth Neoplasms (diagnostic imaging, pathology)
• Neoplasm Invasiveness
• Organotechnetium Compounds
• Technetium Tc 99m Sestamibi
• Tomography, Emission-Computed, Single-Photon