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Treatment of diabetic gustatory sweating with topical glycopyrrolate cream.

Abstract
A 42-year-old insulin-dependent diabetic man presented with severe bilateral gustatory sweating associated with a deterioration in his glycaemic control. Conventional oral antimuscarinic medication was contraindicated because of his cardiac insufficiency. Topical 0.5% glycopyrrolate cream was tried and applied on alternate days to his face, which resulted in the complete cessation of his gustatory sweating without side-effects. Topical glycopyrrolate cream is an effective treatment of diabetic gustatory sweating without the adverse effects commonly found with oral anti-muscarinic medication.
AuthorsS L Atkin, P M Brown
JournalDiabetic medicine : a journal of the British Diabetic Association (Diabet Med) Vol. 13 Issue 5 Pg. 493-4 (May 1996) ISSN: 0742-3071 [Print] England
PMID8737034 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Glycated Hemoglobin A
  • Hypoglycemic Agents
  • Insulin
  • Insulin, Regular, Pork
  • Muscarinic Antagonists
  • insulin, neutral
  • Glycopyrrolate
Topics
  • Administration, Topical
  • Adult
  • Diabetes Mellitus, Type 1 (blood, drug therapy, physiopathology)
  • Glycated Hemoglobin (analysis)
  • Glycopyrrolate (administration & dosage, therapeutic use)
  • Humans
  • Hypoglycemia
  • Hypoglycemic Agents (therapeutic use)
  • Insulin (therapeutic use)
  • Insulin, Regular, Pork
  • Male
  • Muscarinic Antagonists (administration & dosage, therapeutic use)
  • Sweating, Gustatory (drug therapy, etiology)

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