Effectiveness of nedocromil sodium in preventing exercise-induced asthma in children.

Abstract

Exercise-induced asthma is a well-known phenomenon, particularly affecting children, with an important social impact. In order to assess the usefulness of nedocromil sodium in the prevention of exercise-induced asthma, we studied 49 (15 females, 34 males) children who suffered from asthma; their mean +/- SD age was 9.2 +/- 3.0 (range: 3.3-19.1) years. On the first day respiratory function was evaluated by spirometry, basally and after 6 minutes. The inhalation of nedocromil sodium had a great influence on post-exercise lung function measurements; in fact on the day of nedocromil sodium pretreatment, our patients showed an increase of respiratory function, significantly different from the parameters recorded during the first day. Our findings suggest that nedocromil sodium is effective in the prevention of exercise-induced asthma, in pediatric age.

• Authors: A Verrotti, M Verini, S Amadio, G Morgese
• Journal: Panminerva medica (Panminerva Med) Vol. 37 Issue 4 Pg. 210-3 (Dec 1995) ISSN: 0031-0808 [Print] Italy
• PMID: 8710404 (Publication Type: Journal Article)

Chemical References

• Anti-Asthmatic Agents
• Nedocromil

Topics

• Adolescent
• Adult
• Anti-Asthmatic Agents (therapeutic use)
• Asthma, Exercise-Induced (prevention & control)
• Child
• Child, Preschool
• Female
• Humans
• Male
• Nedocromil (therapeutic use)
• Treatment Outcome