Abstract |
Cicatricial pemphigoid is a chronic vesiculobullous disease of the mucosal epithelium that primarily involves the oral cavity and the eyes. The clinical and histologic features are identical to those of bullous pemphigoid, and these features often can be nonspecific for other disease processes. It is not unusual for a period of 1 year or more to elapse before a diagnosis is made. The diagnosis of cicatricial pemphigoid requires characteristic lesions and histopathologic evidence of immunoglobulin deposition along the basement membrane, as well as a high index of suspicion. The authors detail a case of cicatricial pemphigoid resulting in airway obstruction and present the treatment required for both stabilization of the airway and resolution of the disease process.
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Authors | J B Lazor, M A Varvares, W W Montgomery, M L Goodman, B T Mackool |
Journal | The Laryngoscope
(Laryngoscope)
Vol. 106
Issue 8
Pg. 1014-7
(Aug 1996)
ISSN: 0023-852X [Print] United States |
PMID | 8699892
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Anti-Inflammatory Agents
- Glucocorticoids
- Immunoglobulin G
- Immunosuppressive Agents
- Azathioprine
- Prednisone
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Topics |
- Adult
- Airway Obstruction
(drug therapy, surgery, therapy)
- Anti-Inflammatory Agents
(administration & dosage, therapeutic use)
- Azathioprine
(administration & dosage, therapeutic use)
- Chronic Disease
- Diagnosis, Differential
- Fluorescent Antibody Technique, Indirect
- Follow-Up Studies
- Glucocorticoids
(administration & dosage, therapeutic use)
- Humans
- Immunoglobulin G
(analysis)
- Immunosuppressive Agents
(administration & dosage, therapeutic use)
- Male
- Pemphigoid, Benign Mucous Membrane
(complications, diagnosis, therapy)
- Prednisone
(administration & dosage, therapeutic use)
- Time Factors
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