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[Osteosarcoma and Ewing's sarcoma. Improved recovery chances in the past 25 years according to the experience of Balgrist Hospital].

Abstract
At the Balgrist hospital 38 patients with osteosarcoma and 18 patients with Ewing sarcoma were treated from 1970 through 1992; a follow-up of at least three years is available for all patients. Disease-free survival in this period of time has increased from 20% (Ewing sarcoma) and 30% (osteosarcoma) to over 75%. While systemic tumor control was improved by systematic chemotherapy, local tumor control was improved by appropriate biopsy techniques, and amputations have been replaced by local resections, in most cases with reconstruction (arthrodesis, rotation plasty, endoprosthesis, allografts), which require further improvements. With respect to cure of the neoplastic disease, the currently available methods have been used to their maximum potential, and a steady state has been reached regarding survival. Further improvement of survival will therefore depend on the introduction of completely new modalities.
AuthorsG U Exner, A R von Hochstetter, A Schreiber, E Sokolovic-Dalipagic
JournalPraxis (Praxis (Bern 1994)) Vol. 85 Issue 22 Pg. 706-13 (May 28 1996) ISSN: 1661-8157 [Print] Switzerland
Vernacular TitleOsteosarkom und Ewing-Sarkom. Die verbesserten Heilungschancen in den vergangenen 25 Jahren in der Erfahrung der Klinik Balgrist.
PMID8693235 (Publication Type: English Abstract, Journal Article)
Topics
  • Adolescent
  • Bone Neoplasms (drug therapy, pathology, surgery)
  • Child
  • Combined Modality Therapy
  • Disease-Free Survival
  • Female
  • Humans
  • Lung Neoplasms (secondary, surgery)
  • Male
  • Osteosarcoma (drug therapy, pathology, surgery)
  • Sarcoma, Ewing (drug therapy, pathology, surgery)

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