Benzocaine-induced methemoglobinemia.

Abstract

Severe methemoglobinemia developed in a healthy 14-month-old infant following the topical application of a benzocaine-containing gel administered for the relief of the discomfort of teething. Congenital methemoglobinemia and hemoglobin M disease were excluded by appropriate laboratory studies. The patient is considered to have a normal methemoglobin-reducing capacity and her response to the drug is one that presumably could occur in any other child of comparable age on receiving an equivalent dose of benzocaine. Parents should be cautioned against the indiscriminate use of similar medications, particularly since the process for which these medications are administered is both benign and physiologic.

• Authors: P L Townes, M A Geertsma, M R White
• Journal: American journal of diseases of children (1960) (Am J Dis Child) Vol. 131 Issue 6 Pg. 697-8 (Jun 1977) ISSN: 0002-922X [Print] United States
• PMID: 868824 (Publication Type: Case Reports, Journal Article)

Chemical References

• Gels
• Benzocaine

Topics

• Administration, Topical
• Analgesia
• Benzocaine (administration & dosage, adverse effects)
• Female
• Gels
• Humans
• Infant
• Methemoglobinemia (chemically induced)