HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Retrospective analysis on 21 patients with follicular lymphoma].

Abstract
We retrospectively analyzed the clinical data of the 21 patients with follicular lymphoma admitted to our institution from 1977 to 1994. The frequency of follicular lymphoma was 9.1% in the 231 patients with non-Hodgkin's lymphoma. Overall survival rates at 1 year, 3 years, and 5 years were 90.2%, 78.2%, and 52.1%, respectively. The median follow-up of surviving patients and time to treatment failure (TTF) was 43 months and 30 months, respectively. The median time from disease progression to death was 171 days. In univariate analysis, factors associated with poor survival were stage IV (Ann Arbor staging system), anemia (hemoglobin level less than 10g/dl), bone marrow involvement, two or more extranodal sites, and failure in induction of complete remission (CR) in the entire course. Factors associated with short TTF were anemia, bone marrow involvement, and failure in induction of CR. In multivariate analysis, induction of CR affected survival and TTF independently.
AuthorsT Izumi, S Imagawa, K Muroi, R Shimizu, H Takahashi, Y Hoshino, H Tomizuka, T Kawakami, K Toya, H Kurata, J Tsunoda, Y Furukawa, T Suzuki, N Komatsu, A Ohsaka, Y Amemiya, S Takagi, M Yoshida, R Sasaki, K Hatake, Y Miura
Journal[Rinsho ketsueki] The Japanese journal of clinical hematology (Rinsho Ketsueki) Vol. 37 Issue 1 Pg. 7-13 (Jan 1996) ISSN: 0485-1439 [Print] Japan
PMID8683871 (Publication Type: English Abstract, Journal Article)
Topics
  • Adult
  • Aged
  • Bone Marrow Transplantation
  • Female
  • Humans
  • Japan (epidemiology)
  • Lymphoma, Follicular (mortality, pathology, therapy)
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Prognosis
  • Proportional Hazards Models
  • Retrospective Studies
  • Survival Analysis

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: