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[Periodical EEG pattern modifications in herpetic encephalitis treated with acyclovir].

Abstract
The presence of PLED or localized or lateralized periodic activity in encephalitis strongly suggests that the encephalitis is due to the herpes simplex virus. Nevertheless, there has been controversy over its clinical significance. In addition, since the introduction of antiviral drugs in the treatment of herpes encephalitis in its initial stages, the prognosis of the disease has improved. We studied nine patients all diagnosed as having herpes encephalitis and treated with acyclovir. The presence or absence of periodic activity and its characteristics were analyzed. It was seen that either there was no such activity, or if there was, it was not exactly as classically described.
AuthorsA Benetó, E Gómez, P Rubio, R Sobrino, A Esparza, M Gil, M Entrambasaguas, R Valdivieso
JournalRevista de neurologia (Rev Neurol) Vol. 24 Issue 131 Pg. 829-32 (Jul 1996) ISSN: 0210-0010 [Print] Spain
Vernacular TitleModificaciones del patrón EEG periódico en las encefalitis herpéticas tratadas con aciclovir.
PMID8681195 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Antiviral Agents
  • Acyclovir
Topics
  • Acyclovir (administration & dosage, therapeutic use)
  • Adolescent
  • Adult
  • Aged
  • Antiviral Agents (administration & dosage, therapeutic use)
  • Brain (physiopathology, virology)
  • Electroencephalography
  • Encephalitis, Viral (drug therapy, physiopathology, virology)
  • Female
  • Humans
  • Male
  • Middle Aged
  • Simplexvirus (isolation & purification)

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