Prolonged remission of SLE-associated polyradiculoneuropathy after a single course of intravenous immunoglobulin.

Abstract

Polyradiculoneuropathy is a rare and potentially severe complication of systemic lupus erythematosus (SLE). Treatment is not codified and response to corticosteroid is inconstant. We report the case of a patient with severe SLE-associated polyradiculoneuropathy and autoimmune thrombocytopenia. Dramatic neurologic improvement and correction of thrombocytopenia were observed after a single course of high-dose intravenous immunoglobulin infusions (IVIg, 2g/kg body weight). Our case suggests that IVIg may be effective in the treatment of this unusual condition.

• Authors: P Lesprit, F Mouloud, P Bierling, A Schaeffer, P Cesaro, C Brun-Buisson, B Godeau
• Journal: Scandinavian journal of rheumatology (Scand J Rheumatol) Vol. 25 Issue 3 Pg. 177-9 ( 1996) ISSN: 0300-9742 [Print] England
• PMID: 8668963 (Publication Type: Case Reports, Journal Article)

Chemical References

• Immunoglobulins, Intravenous

Topics

• Aged
• Aged, 80 and over
• Humans
• Immunoglobulins, Intravenous (administration & dosage)
• Lupus Erythematosus, Systemic (complications)
• Male
• Polyradiculoneuropathy (complications, therapy)
• Purpura, Thrombocytopenic, Idiopathic (complications, therapy)
• Remission Induction
• Time Factors