Abstract |
Many human genes associated with disease have close homologs in yeast. Based on this homology, many human proteins have been studied using yeast expression systems. This paper will review research done in our laboratory using a yeast expression system to study the human protein galactose-1-phosphate uridylyltransferase, associated with galactosemia, as well as highlighting some of the advantages of this model system.
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Authors | L Wells, J L Fridovich-Keil |
Journal | SAAS bulletin, biochemistry and biotechnology
(SAAS Bull Biochem Biotechnol)
Vol. 9
Pg. 83-8
( 1996)
ISSN: 1052-6781 [Print] United States |
PMID | 8652137
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S., Review)
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Chemical References |
- UTP-Hexose-1-Phosphate Uridylyltransferase
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Topics |
- Galactosemias
(enzymology)
- Humans
- Models, Biological
- Saccharomyces cerevisiae
(genetics)
- UTP-Hexose-1-Phosphate Uridylyltransferase
(genetics)
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