[The effect of prolonged starvation on changes in the activity of selected adaptive enzymes in rat liver].

Abstract

Male rats of Wistar SPF stain (Velaz Prague) were used to investigate the influence of prolonged starvation on changes in the activity of selected adaptive enzymes in the liver and corticosterone in serum. Analyses were carried out on days 1,2,3,5 and 7 of starvation. The activity of tyrosine aminotransferase significantly increased in the period between days 2 and 5 of starvation, after which a decrease to the level of satiated animals was observed in the terminal period. Activities of tryptophane-2-3-dioxygenase and alanine aminotransferase increased in two phases reaching maximum values on days 2 and 7 of starvation. The activity of aspartate aminotransferase showed a progressive significant increase in dependence on the length of starvation. A more than threefold increase in corticosterone concentration was observed in the serum of starved animals in comparison with satiated rats.

• Authors: M Toropila, I Ahlers, E Ahlersová, M Ondrasovic, K Benová
• Journal: Veterinarni medicina (Vet Med (Praha)) Vol. 41 Issue 2 Pg. 41-4 (Feb 1996) ISSN: 0375-8427 [Print] Czech Republic
• Vernacular Title: Vplyv prolongovaného hladovania na zmeny aktivity vybraných adaptívnych enzýmov v peceni potkanov.
• PMID: 8629317 (Publication Type: English Abstract, Journal Article)

Chemical References

• Tryptophan Oxygenase
• Aspartate Aminotransferases
• Alanine Transaminase
• Tyrosine Transaminase
• Corticosterone

Topics

• Alanine Transaminase (metabolism)
• Animals
• Aspartate Aminotransferases (metabolism)
• Corticosterone (blood)
• Liver (enzymology)
• Male
• Rats
• Rats, Wistar
• Starvation (blood, enzymology)
• Tryptophan Oxygenase (metabolism)
• Tyrosine Transaminase (metabolism)