Endoscopic treatment of vesicoureteral reflux with collagen: preliminary report and cost analysis.

Abstract

PURPOSE:

We determined therapeutic and operative cost efficacy of endoscopic collagen injection for vesicoureteral reflux.

MATERIALS AND METHODS:

We performed a multicenter study of 10 male and 23 female sequential patients (45 renal units) with vesicoureteral reflux and a surgical indication. Patients were skin tested with collagen and when negative, they underwent endoscopic injection. Renal ultrasound/cystography was done 3 months after treatment. Cost analysis was performed at 1 institution.

RESULTS:

Reflux was grade I in 2 renal units, II in 18, III in 15 and IV in 10. The majority of cases were single systems with primary reflux. We performed 1 treatment in 32 renal units, 2 in 6, 3 in 6 and 4 in 1. Cure was evident in 31 of 38 renal units (81.6%) and 21 of 27 patients (78%) 3 months after the last injection. Patient morbidity was minimal. Operative cost per renal unit was $1,599.68 for collagen injection and $9,144.47 for reimplantation.

CONCLUSIONS:

Endoscopic injection of collagen is effective treatment for vesicoureteral reflux. Furthermore, it causes minimal morbidity and may effect cost savings in health care management.

• Authors: M P Leonard, A Decter, L W Mix, H W Johnson, G U Coleman
• Journal: The Journal of urology (J Urol) Vol. 155 Issue 5 Pg. 1716-20 (May 1996) ISSN: 0022-5347 [Print] United States
• PMID: 8627868 (Publication Type: Clinical Trial, Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't)

Chemical References

• Collagen

Topics

• Adolescent
• Child
• Child, Preschool
• Collagen (therapeutic use)
• Costs and Cost Analysis
• Endoscopy
• Female
• Humans
• Infant
• Male
• Prostheses and Implants (economics)
• Vesico-Ureteral Reflux (economics, therapy)