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Hyperandrogenism, insulin resistance, and acanthosis nigricans (HAIR-AN) syndrome: spontaneous remission in a 15-year-old girl.

Abstract
Acanthosis nigricans is associated with many diseases, including internal malignancies, genetic disorders, and endocrine abnormalities. Insulin resistance frequently accompanies endocrine-associated acanthosis nigricans. We describe a patient with acanthosis nigricans associated with hyperandrogenism and extreme insulin resistance that spontaneously resolved after a marked decrease in insulin receptor antibodies.
AuthorsL E Esperanza, N A Fenske
JournalJournal of the American Academy of Dermatology (J Am Acad Dermatol) Vol. 34 Issue 5 Pt 2 Pg. 892-7 (May 1996) ISSN: 0190-9622 [Print] United States
PMID8621823 (Publication Type: Case Reports, Journal Article)
Topics
  • Acanthosis Nigricans (etiology, pathology, physiopathology)
  • Adolescent
  • Female
  • Humans
  • Hyperandrogenism (etiology, pathology, physiopathology)
  • Insulin Resistance
  • Remission, Spontaneous
  • Skin (pathology)
  • Syndrome

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