Abstract |
The therapeutic efficacy of short-term treatment with a 1% cream of lanoconazole, a new imidazole antimycotic agent, in comparison with that of a 1% cream of terbinafine was evaluated in the guinea pig model of tinea pedis. Each agent was topically applied once a day for 3 or 7 consecutive days, starting on day 10 postinfection, and a culture study was conducted on day 5 after the last treatment with each agent. The 1% cream of lanoconazole was as highly effective as the 1% cream of terbinafine in terms of eradicating the fungi from the infected feet.
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Authors | Y Niwano, T Tabuchi, K Kanai, H Hamaguchi, K Uchida, H Yamaguchi |
Journal | Antimicrobial agents and chemotherapy
(Antimicrob Agents Chemother)
Vol. 39
Issue 10
Pg. 2353-5
(Oct 1995)
ISSN: 0066-4804 [Print] United States |
PMID | 8619597
(Publication Type: Journal Article)
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Chemical References |
- Antifungal Agents
- Heterocyclic Compounds
- Imidazoles
- latoconazole
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Topics |
- Administration, Topical
- Animals
- Antifungal Agents
(therapeutic use)
- Guinea Pigs
- Heterocyclic Compounds
(therapeutic use)
- Imidazoles
(therapeutic use)
- Male
- Tinea Pedis
(drug therapy, pathology)
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