Case report: successful treatment with cimetidine and zinc sulphate in chronic mucocutaneous candidiasis.

Abstract

The authors evaluated the clinical efficacy of a treatment with cimetidine and zinc sulphate in a patient with chronic mucocutaneous candidiasis. Cimetidine was given at a dose of 400 mg three times daily; zinc sulphate at a dose of 200 mg daily, then adjusted to maintain blood zinc levels at the upper normal range. This treatment lasted 16 months. An impressive and significant reduction of the infectious events and an increased CD4 (helper/inducer) cell counts were observed. The authors conclude that this combined immunopotentiating treatment is safe and inexpensive to treat immunodeficiency disorders.

• Authors: B Polizzi, L Origgi, G Zuccaro, P Matti, R Scorza
• Journal: The American journal of the medical sciences (Am J Med Sci) Vol. 311 Issue 4 Pg. 189-90 (Apr 1996) ISSN: 0002-9629 [Print] United States
• PMID: 8602650 (Publication Type: Case Reports, Journal Article)

Chemical References

• Adjuvants, Immunologic
• Sulfates
• Zinc Compounds
• Zinc Sulfate
• Cimetidine

Topics

• Adjuvants, Immunologic (therapeutic use)
• Adult
• CD4 Lymphocyte Count (drug effects)
• Candidiasis, Chronic Mucocutaneous (blood, drug therapy)
• Cimetidine (therapeutic use)
• Female
• Humans
• Sulfates (therapeutic use)
• Zinc Compounds (therapeutic use)
• Zinc Sulfate