Abstract |
A pestivirus isolated from a healthy pig out of a mixed pig-cattle holding was identified by use of monoclonal antibodies as a porcine virus related or identical to bovine viral diarrhoea (BVD) virus. About 7% of the pigs of this herd showed neutralizing antibodies (nab) against BVD and Border Disease (BD) virus and against the homologous porcine nonclassical swine fever (CSF) pestivirus isolate 10421/Han94. The nab titres against this virus were clearly higher than against CSF virus strain Alfort/187. Amongst the cattle kept in the farm no BVD viraemic animal was detected. About 13% of them showed nab to BVD virus with higher titres against the BVD virus strain NADL than against the porcine pestivirus virus isolate 10421/Han94. There was no of a BVD virus transmission from the cattle to the pigs within this herd. The problem of misinterpretation of non-CSF virus isolation from pigs is discussed. The necessity of identifying pestiviruses of porcine origin by use of species-specific monoclonal antibodies is stressed in order to prevent erroneous declarations of CSF outbreaks.
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Authors | H R Frey, B Röder, K Depner, B Liess |
Journal | DTW. Deutsche tierarztliche Wochenschrift
(Dtsch Tierarztl Wochenschr)
Vol. 102
Issue 5
Pg. 181-3
(May 1995)
ISSN: 0341-6593 [Print] Germany |
Vernacular Title | Epidemiologische Charakterisierung eines Pestivirus-Isolates von einem virämischen Schwein in einem gemischten Schweine-Rinderbestand. |
PMID | 8593767
(Publication Type: Case Reports, English Abstract, Journal Article)
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Chemical References |
- Antibodies, Monoclonal
- Antibodies, Viral
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Topics |
- Animal Husbandry
- Animals
- Antibodies, Monoclonal
- Antibodies, Viral
(blood)
- Bovine Virus Diarrhea-Mucosal Disease
(transmission)
- Cattle
- Diarrhea
(veterinary, virology)
- Pestivirus
(isolation & purification)
- Pestivirus Infections
(diagnosis, veterinary)
- Swine
(virology)
- Swine Diseases
- Viremia
(veterinary, virology)
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