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[Epidemiological characterization of a pestivirus isolate from a viremic pig out of a mixed pig-cattle herd].

Abstract
A pestivirus isolated from a healthy pig out of a mixed pig-cattle holding was identified by use of monoclonal antibodies as a porcine virus related or identical to bovine viral diarrhoea (BVD) virus. About 7% of the pigs of this herd showed neutralizing antibodies (nab) against BVD and Border Disease (BD) virus and against the homologous porcine nonclassical swine fever (CSF) pestivirus isolate 10421/Han94. The nab titres against this virus were clearly higher than against CSF virus strain Alfort/187. Amongst the cattle kept in the farm no BVD viraemic animal was detected. About 13% of them showed nab to BVD virus with higher titres against the BVD virus strain NADL than against the porcine pestivirus virus isolate 10421/Han94. There was no of a BVD virus transmission from the cattle to the pigs within this herd. The problem of misinterpretation of non-CSF virus isolation from pigs is discussed. The necessity of identifying pestiviruses of porcine origin by use of species-specific monoclonal antibodies is stressed in order to prevent erroneous declarations of CSF outbreaks.
AuthorsH R Frey, B Röder, K Depner, B Liess
JournalDTW. Deutsche tierarztliche Wochenschrift (Dtsch Tierarztl Wochenschr) Vol. 102 Issue 5 Pg. 181-3 (May 1995) ISSN: 0341-6593 [Print] Germany
Vernacular TitleEpidemiologische Charakterisierung eines Pestivirus-Isolates von einem virämischen Schwein in einem gemischten Schweine-Rinderbestand.
PMID8593767 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Antibodies, Monoclonal
  • Antibodies, Viral
Topics
  • Animal Husbandry
  • Animals
  • Antibodies, Monoclonal
  • Antibodies, Viral (blood)
  • Bovine Virus Diarrhea-Mucosal Disease (transmission)
  • Cattle
  • Diarrhea (veterinary, virology)
  • Pestivirus (isolation & purification)
  • Pestivirus Infections (diagnosis, veterinary)
  • Swine (virology)
  • Swine Diseases
  • Viremia (veterinary, virology)

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