HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Antimicrobial oligopeptides--an important factor in non-specific defense against infection].

Abstract
For survival of plants, animals as well as main in a nature full of aggressive microbes, endogenous antibiotics play an essential role, which is not yet fully appreciated in medicine and science. For example in the granules of polymorphonuclear granulocytes and macrophages or even of specialized epithelial cells such as Paneth cells in the crypts of the intestinal mucosa, oligopeptides are produced with a wide range of antimicrobial activity. According to their chemical structures and modes of action they can be grouped into various different families. The physiological role of these agents on the surface of skin and mucosa or within host tissue is only incompletely understood.
AuthorsB Haegele, V Mersch-Sundermann, M Kretschmar, H Hof
JournalImmunitat und Infektion (Immun Infekt) Vol. 23 Issue 6 Pg. 205-8 (Dec 1995) Germany
Vernacular TitleAntimikrobiell wirksame Oligopeptide--ein wichtiger Teil der unspezifischen Infektabwehr.
PMID8582735 (Publication Type: Journal Article, Review)
Chemical References
  • Oligopeptides
Topics
  • Bacteria (drug effects)
  • Bacterial Infections (prevention & control)
  • Granulocytes
  • Humans
  • Infection Control (methods)
  • Intestinal Mucosa (chemistry, microbiology)
  • Neutrophils
  • Oligopeptides (chemistry, classification, metabolism, pharmacology)
  • Skin (microbiology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: