[Apudoma of the prostate].

Abstract

Prostatic apudomas are represented by well-, moderately- and poorly differentiated variants. Histologic differentiation determines various functional properties of tumor cells. Tumor cells of well-differentiated apudomas produce serotonin, less frequently calcitonin, poorly differentiated ones produce only ACTH. Apud cells of moderately differentiated tumors, besides their main function to synthesize biogenic amines and hormones (serotonin, ACTH) possess immunoreactivity to epithelial membrane antigen, carcinoembryonal antigen and prostatic specific antigen.

• Authors: B S Serezhin
• Journal: Arkhiv patologii (Arkh Patol) 1995 Sep-Oct Vol. 57 Issue 5 Pg. 57-63 ISSN: 0004-1955 [Print] Russia (Federation)
• Vernacular Title: Apudomy predstatel'noĭ zhelezy.
• PMID: 8579498 (Publication Type: English Abstract, Journal Article)

Chemical References

• Carcinoembryonic Antigen
• Serotonin
• Adrenocorticotropic Hormone
• Calcitonin
• Prostate-Specific Antigen

Topics

• APUD Cells (pathology)
• Adrenocorticotropic Hormone (biosynthesis)
• Apudoma (immunology, metabolism, pathology)
• Calcitonin (biosynthesis)
• Carcinoembryonic Antigen (analysis)
• Cell Differentiation (physiology)
• Humans
• Immunohistochemistry
• Male
• Prostate-Specific Antigen (analysis)
• Prostatic Neoplasms (immunology, metabolism, pathology)
• Serotonin (biosynthesis)