Abstract | OBJECTIVE: DESIGN: Prospective, randomized, clinical study. ANIMALS: 16 traumatized adult dogs with clinical signs of shock. PROCEDURE: Physical, hemodynamic, blood gas, and clinical chemistry measurements were performed prior to treatment. Initial treatment consisted of HSD (n = 8) or LRS (n = 8) administered as a bolus (5 ml/kg of body weight, IV) over a 3-minute period, followed by administration of additional LRS and other treatments to restore hemodynamic and physical criteria to within reference limits. Measurements were repeated for 3 hours after initial treatment. The volumes of LRS and HSD administered were recorded hourly. Degree of injury was scored by using a trauma severity index. RESULTS: Dogs responded similarly to the treatments, and all but 3 dogs survived to be discharged. The amount of fluid administered to dogs in the HSD group over the final 2 hours of the study was significantly less than that administered to the dogs in the LRS group. Serum sodium concentration and osmolality of the dogs in the HSD group were not significantly greater than those values in the LRS group. Bradyarrhythmias were observed in 2 dogs in the HSD group. CLINICAL IMPLICATIONS:
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Authors | E R Schertel, D A Allen, W W Muir, B D Hansen |
Journal | Journal of the American Veterinary Medical Association
(J Am Vet Med Assoc)
Vol. 208
Issue 3
Pg. 366-70
(Feb 01 1996)
ISSN: 0003-1488 [Print] United States |
PMID | 8575966
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Dextrans
- Isotonic Solutions
- Plasma Substitutes
- Ringer's Lactate
- Saline Solution, Hypertonic
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Topics |
- Accidents, Traffic
- Animals
- Dextrans
(therapeutic use)
- Dog Diseases
(therapy)
- Dogs
(injuries)
- Fluid Therapy
(veterinary)
- Isotonic Solutions
(therapeutic use)
- Plasma Substitutes
(therapeutic use)
- Prospective Studies
- Ringer's Lactate
- Saline Solution, Hypertonic
(therapeutic use)
- Shock, Traumatic
(therapy, veterinary)
- Trauma Severity Indices
- Treatment Outcome
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