Ofloxacin eardrop treatment for active chronic suppurative otitis media: prospective randomized study.

Abstract

This report presents a prospective randomized study of 0.3 percent ofloxacin eardrops for the treatment of active chronic suppurative otitis media. Twenty-nine patients were treated with ofloxacin eardrops for 1 week, and another 27 patients were treated with Augmentin for 1 week. One week after completion of treatment, 22 (76%) patients of the group treated with ofloxacin had dry ears, and only seven (26%) patients treated with Augmentin had dry ears. Ofloxacin eardrops were effective in the initial treatment of active chronic suppurative otitis media.

• Authors: P W Yuen, S K Lau, P Y Chau, Y Hui, S F Wong, S Wong, W I Wei
• Journal: The American journal of otology (Am J Otol) Vol. 15 Issue 5 Pg. 670-3 (Sep 1994) ISSN: 0192-9763 [Print] United States
• PMID: 8572070 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Anti-Infective Agents
• Clavulanic Acids
• Amoxicillin-Potassium Clavulanate Combination
• Amoxicillin
• Ofloxacin

Topics

• Administration, Oral
• Adolescent
• Adult
• Aged
• Amoxicillin (therapeutic use)
• Amoxicillin-Potassium Clavulanate Combination
• Anti-Infective Agents (therapeutic use)
• Chronic Disease
• Clavulanic Acids (therapeutic use)
• Drug Therapy, Combination (therapeutic use)
• Female
• Humans
• Instillation, Drug
• Male
• Middle Aged
• Ofloxacin (therapeutic use)
• Otitis Media, Suppurative (drug therapy, microbiology)
• Prospective Studies
• Severity of Illness Index