Reproductive ability of an adult female with Silver-Russell syndrome.

Abstract

An adult female with typical features of Silver-Russell dwarfism gave birth to a viable infant. Despite the abnormalities in sexual development that may be associated with the Silver-Russell syndrome, fertility is not necessarily impaired, at least in females. The growth and development of children with the Silver-Russell syndrome have been studied (Silver, 1964; Tanner et al., 1975). There is, however, virtually no information available about adult patients with this syndrome. It is known that both male and female Silver-Russell dwarfs develop secondary sexual characteristics (Rimoin, 1969; McDowell and Sproles, 1973) but fertility of these patients has not been described previously.

• Authors: H K Abramowicz, H M Nitowsky
• Journal: Journal of medical genetics (J Med Genet) Vol. 14 Issue 2 Pg. 134-6 (Apr 1977) ISSN: 0022-2593 [Print] England
• PMID: 856957 (Publication Type: Case Reports, Journal Article, Research Support, U.S. Gov't, P.H.S.)

Chemical References

• Gonadotropins

Topics

• Adult
• Dermatoglyphics
• Dwarfism (complications, genetics, physiopathology)
• Female
• Fertility
• Gonadotropins (urine)
• Humans
• Syndrome
• Wolff-Parkinson-White Syndrome (complications)