New discriminatory level for glucosidase activity to diagnose epididymal obstruction or dysfunction.

Abstract

Neutral alpha-glucosidase activity was measured in seminal plasma of 30 patients consulting for infertility with a variety of disorders, and compared with 25 normal controls. Significantly more of the study populations (asthenozoospermia, 4/6; oligozoospermia, 3/5; azoospermia 8/15) had a neutral alpha-glucosidase activity less than 10 mIU/mL as compared with control samples (3/25). Also the mean (+/- SD) neutral alpha-glucosidase activity in patients with asthenozoospermia (11.7 +/- 9.2) oligozoospermia (11.3 +/- 7.2), and post vasectomy azoospermia (5.3 +/- 3.4) was significantly (p < .05) less than ejaculate from controls (21.2 +/- 14). A seminal alpha-glucosidase level of 10 mIU/mL appears to be a useful discriminatory marker in the diagnosis of epididymal obstruction or dysfunction.

• Authors: B Kret, M Milad, R S Jeyendran
• Journal: Archives of andrology (Arch Androl) 1995 Jul-Aug Vol. 35 Issue 1 Pg. 29-33 ISSN: 0148-5016 [Print] England
• PMID: 8554428 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Biomarkers
• alpha-Glucosidases

Topics

• Biomarkers (analysis)
• Clinical Enzyme Tests
• Epididymis
• Humans
• Infertility, Male (diagnosis, enzymology, etiology)
• Male
• Oligospermia (diagnosis, enzymology, etiology)
• Reference Values
• Semen (enzymology)
• Testicular Diseases (diagnosis, enzymology)
• alpha-Glucosidases (analysis, metabolism)