Occupational allergic contact dermatitis caused by epoxy diacrylate in ultraviolet-light-cured paint, and bisphenol A in dental composite resin.

Abstract

Allergic contact dermatitis (ACD) caused by epoxy di(meth)acrylates or bisphenol A is rare. Here 2 such cases are reported. A dental assistant had allergic contact dermatitis (ACD) caused by bisphenol A contained in dental composite resin (DCR) products based on epoxy dimethacrylate. The contact allergy was verified by allergic patch test reactions to bisphenol A and 2 DCRs. The DCRs giving allergic reactions were analyzed, and 0.014-0.015% of bisphenol A was detected. Occupational ACD caused by bisphenol A in dental composite resins has not been described before. The other patient was a male process worker in a paint factory. He was sensitized by an epoxy diacrylate, 2,2-bis[4-(2-hydroxy-3-acryloxypropoxy)phenyl]-propane (BIS-GA), and other acrylate compounds contained in raw materials of ultraviolet-light-curable paint. The epoxy diacrylate gave an allergic patch test reaction down to 0.016% in pet. He also had an allergic patch test reaction to several other acrylate compounds, 2-hydroxyethyl acrylate, 2-hydroxypropyl acrylate, 1,4-butanediol diacrylate, 1,6-hexanediol diacrylate, diethyleneglycol diacrylate, triethylene glycol diacrylate, and tripropylene glycol diacrylate, indicating cross and/or concomitant sensitization.

• Authors: R Jolanki, L Kanerva, T Estlander
• Journal: Contact dermatitis (Contact Dermatitis) Vol. 33 Issue 2 Pg. 94-9 (Aug 1995) ISSN: 0105-1873 [Print] England
• PMID: 8549151 (Publication Type: Case Reports, Journal Article)

Chemical References

• 2,2-bis(4-(2-hydroxy-3-acryloxypropoxy)phenyl)propane
• Acrylates
• Benzhydryl Compounds
• Dental Materials
• Epoxy Resins
• Phenols
• bisphenol A epoxy resin diacrylate ester
• bisphenol A

Topics

• Acrylates (adverse effects, chemistry)
• Adult
• Benzhydryl Compounds
• Chemical Industry
• Dental Materials (adverse effects)
• Dental Technicians
• Dermatitis, Allergic Contact (etiology, physiopathology, therapy)
• Dermatitis, Occupational (etiology, physiopathology, therapy)
• Epoxy Resins (adverse effects, chemistry)
• Female
• Hand Dermatoses (etiology)
• Humans
• Male
• Paint (adverse effects)
• Patch Tests
• Phenols (adverse effects, chemistry)
• Ultraviolet Rays