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Epidemic spread of plasmid-mediated tetracycline resistant Neisseria gonorrhoeae in Zaire.

Abstract
A cohort of 650 prostitutes from Kinshasa, Zaire, was followed at monthly intervals for sexually transmitted diseases as part of an HIV intervention project. Neisseria gonorrhoeae isolates, obtained during a period of 30 months, were auxotyped, serotyped and tested for antimicrobial susceptibility. Among 1085 gonococcal isolates tested, 725 (67%) produced beta-lactamase (PPNG) and 323 (30%) showed plasmid-mediated resistance to tetracyline (TRNG). Over time, the prevalence of PPNG varied between 60 and 73%, while the level of TRNG increased from 11 to 45%.
AuthorsE Van Dyck, M Laga, A T Manoka, F Behets, P Piot
JournalInternational journal of STD & AIDS (Int J STD AIDS) Vol. 6 Issue 5 Pg. 345-7 ( 1995) ISSN: 0956-4624 [Print] England
PMID8547415 (Publication Type: Journal Article)
Topics
  • Democratic Republic of the Congo (epidemiology)
  • Female
  • Follow-Up Studies
  • Gonorrhea (epidemiology, microbiology)
  • Humans
  • Microbial Sensitivity Tests
  • Neisseria gonorrhoeae (classification)
  • Population Surveillance
  • Prevalence
  • R Factors
  • Serotyping
  • Sex Work
  • Tetracycline Resistance
  • Urban Health

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