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Randomised comparison of silicone versus Teflon cannulas for peripheral intravenous nutrition.

Abstract
The use of peripheral intravenous nutrition using standard Teflon cannulas is limited by a high incidence of thrombophlebitis, with resultant frequent line changes and compromised nutritional therapy. Fine-bore silicone catheters may reduce the incidence of thrombophlebitis; we prospectively compared the silicone catheter with a Teflon cannula in a randomised trial. Seventy-nine surgical patients were randomised to receive peripheral nutrition (10 g nitrogen; 1770 kcal; 650 mOsm/l) either via a Teflon cannula (18G, 4.4 cm long) or via a silicone catheter (23G, 15 cm long). Compared with the group randomised to a standard Teflon cannula, patients fed via a silicone catheter had a significant (P < 0.001) improvement in (a) median time to survival of the first catheter (125 h vs 48 h); (b) incidence of catheter reinsertions (13% vs 75%); and (c) incidence of thrombophlebitis (10% vs 48%). Delivery of a moderately hypertonic nutritional solution through a fine-bore silicone catheter is safe, durable and well tolerated, with a low incidence of complications relative to a Teflon cannula. An expanded role for this catheter in nutritional therapy is feasible, which may reduce the requirement for central venous parenteral nutrition.
AuthorsJ V Reynolds, K Walsh, J Ruigrok, J M Hyland
JournalAnnals of the Royal College of Surgeons of England (Ann R Coll Surg Engl) Vol. 77 Issue 6 Pg. 447-9 (Nov 1995) ISSN: 0035-8843 [Print] England
PMID8540665 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
Chemical References
  • Silicone Elastomers
  • Polytetrafluoroethylene
Topics
  • Adult
  • Aged
  • Aged, 80 and over
  • Catheterization, Peripheral (adverse effects, instrumentation)
  • Catheters, Indwelling
  • Female
  • Humans
  • Male
  • Middle Aged
  • Parenteral Nutrition (instrumentation)
  • Polytetrafluoroethylene
  • Silicone Elastomers
  • Thrombophlebitis (etiology)

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