Langerhans' cell histiocytosis: possible association with malignant germ cell tumour.

Abstract

A rare case of adult onset Langerhans' cell histiocytosis associated with dysgerminoma in a 35 year old Chinese woman is reported. The patient had a history of dysgerminoma of left ovary 15 years previously and had undergone surgery followed by radiotherapy and an uneventful recovery. She presented again in March 1994, this time with a left clavicular mass, which was shown histologically to be Langerhans' cell histiocytosis. The report illustrates the probable association between the two lesions, with some discussion on the underlying pathogenesis.

• Authors: W K Ng, K Y Lam, I O Ng
• Journal: Journal of clinical pathology (J Clin Pathol) Vol. 48 Issue 10 Pg. 963-5 (Oct 1995) ISSN: 0021-9746 [Print] England
• PMID: 8537500 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Dysgerminoma (complications, pathology)
• Female
• Histiocytosis, Langerhans-Cell (complications, pathology)
• Humans
• Ovarian Neoplasms (complications, pathology)