Reversible ophthalmoplegia in CPEO.

Abstract

PURPOSE:

To present a case of improvement of ocular motility in a patient with chronic progressive external ophthalmoplegia (CPEO) with Coenzyme Q10.

METHODS:

Coenzyme Q10 300 mg daily was given for three years with a three-day trial period of 200 mg daily after one year. Ocular ductions were measured by synoptophore.

RESULTS:

Ocular ductions improved with treatment with Coenzyme Q10.

CONCLUSION:

Coenzyme Q10, is effective in limiting the severity of ophthalmoplegia in this case.

• Authors: I S Dunlop, P Dunlop
• Journal: Australian and New Zealand journal of ophthalmology (Aust N Z J Ophthalmol) Vol. 23 Issue 3 Pg. 231-4 (Aug 1995) ISSN: 0814-9763 [Print] Australia
• PMID: 8534451 (Publication Type: Case Reports, Journal Article)

Chemical References

• Coenzymes
• Ubiquinone
• coenzyme Q10

Topics

• Adult
• Chronic Disease
• Coenzymes
• Dose-Response Relationship, Drug
• Drug Administration Schedule
• Eye Movements
• Female
• Humans
• Kearns-Sayre Syndrome (complications)
• Ophthalmoplegia (complications, drug therapy)
• Ubiquinone (administration & dosage, analogs & derivatives, therapeutic use)