Abstract |
Clostridium botulinum A exotoxin ( Botox) is the most potent toxin known to man. It produces a reversible paralysis of cholinergically innervated muscle, an effect useful in the management of non-accommodative strabismus and various disabling focal dystonias. In the present study, botulinum toxin ( Botox) was used to treat congenital nystagmus, injecting the toxin into multiple horizontal rectus muscles at the same treatment session. Three of four patients achieved a significant enough change in acuity to receive daytime-restricted driver's licenses. No treatment was complicated by retrobulbar hemorrhage, ocular perforation, or ptosis. Two patients are continuing the Botox treatments every 3 to 4 months.
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Authors | J Carruthers |
Journal | Journal of pediatric ophthalmology and strabismus
(J Pediatr Ophthalmol Strabismus)
1995 Sep-Oct
Vol. 32
Issue 5
Pg. 306-8
ISSN: 0191-3913 [Print] United States |
PMID | 8531035
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Adolescent
- Adult
- Botulinum Toxins
(therapeutic use)
- Female
- Humans
- Male
- Nystagmus, Pathologic
(congenital, therapy)
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