[Prognostic factors and their importance in the modification of therapeutic approaches in patients with Hodgkin's disease].

Abstract

A prognostic study was performed in a group of 236 long-term followed patients. Eleven factors in total were included into a multivariate analysis--they were global, clinical and therapeutical factors. For complete remission, clinical stage, age at the time of diagnosis and size of affliction of mediastinum are important. Signs of poor prognosis for complete remission are "bulky" mediastinal disease, male sex and absence or reduction of chemotherapy in primary treatment. Prognostic factors as to the total survival are age at the time of diagnosis, clinical stage, total number and size of afflicted lymphatic areas and absence or reduction of chemotherapy in primary treatment. Emphasis is laid upon evaluation of the amount of individual risk to adjust therapeutic procedures to every individual patient.

• Authors: E Vernerová, P Tesarová, Z Hermanská, Z Dienstbier, P Chytrý
• Journal: Casopis lekaru ceskych (Cas Lek Cesk) Vol. 132 Issue 9 Pg. 266-9 (May 04 1993) ISSN: 0008-7335 [Print] Czech Republic
• Vernacular Title: Prognostické faktory a jejich význam pro modifikaci lécebného postupu u nemocných s Hodgkinovou chorobou.
• PMID: 8513472 (Publication Type: English Abstract, Journal Article)

Topics

• Adolescent
• Adult
• Aged
• Female
• Hodgkin Disease (drug therapy, mortality, pathology)
• Humans
• Male
• Middle Aged
• Prognosis