Splenic infarction associated with anticardiolipin antibodies in a patient with acquired immunodeficiency syndrome.

Abstract

Although patients with AIDS frequently develop high titers of anticardiolipin antibodies, the clinical significance of this laboratory abnormality in AIDS patients is unknown. A 33-year-old female with AIDS, a prior small cerebrovascular accident, thrombocytopenia, and a coagulopathy suddenly developed left upper quadrant pain and tenderness due to splenic infarction associated with a high titer of anticardiolipin antibodies. Possible clinical manifestations of anticardiolipin antibodies in this patient include recurrent thromboembolism, coagulopathy, and thrombocytopenia. This case report suggests that anticardiolipin antibodies are associated with splenic infarction and that anticardiolipin antibodies associated with AIDS may sometimes be clinically significant.

• Authors: M S Cappell, T Simon, M Tiku
• Journal: Digestive diseases and sciences (Dig Dis Sci) Vol. 38 Issue 6 Pg. 1152-5 (Jun 1993) ISSN: 0163-2116 [Print] United States
• PMID: 8508712 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antibodies, Anticardiolipin

Topics

• Acquired Immunodeficiency Syndrome (complications, diagnosis)
• Adult
• Antibodies, Anticardiolipin (blood)
• Blood Coagulation Disorders (diagnosis, etiology)
• Female
• HIV-1
• Humans
• Splenic Infarction (diagnosis, etiology)
• Thrombocytopenia (diagnosis, etiology)