Abstract | OBJECTIVE: DESIGN: Prospective, randomized, controlled trial. SUBJECTS: Thirty-one male Wistar rats. INTERVENTIONS: MEASUREMENTS AND MAIN RESULTS: After the decapitation, the specific gravities of the neocortex, caudatoputamen, hippocampus, cerebellum, and midbrain were measured using a variable-density bromobenzene- kerosene column technique as an index of brain swelling. The specific gravities of the hippocampus and the neocortex were significantly lower in the ischemic group than in the control group. Specific gravities of the caudatoputamen and neocortex in the ischemia plus hypercapnia group, and specific gravities of the caudatoputamen, neocortex, and hippocampus in the ischemia plus hypercapnia group, were significantly lower than in the ischemia group. CONCLUSIONS:
|
Authors | Y Morimoto, T Yamamura, O Kemmotsu |
Journal | Critical care medicine
(Crit Care Med)
Vol. 21
Issue 6
Pg. 907-13
(Jun 1993)
ISSN: 0090-3493 [Print] United States |
PMID | 8504661
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
|
Chemical References |
|
Topics |
- Acidosis, Respiratory
(blood, complications, pathology)
- Animals
- Blood Glucose
(analysis)
- Body Water
(chemistry)
- Brain Chemistry
- Brain Edema
(blood, complications, pathology)
- Brain Ischemia
(blood, complications, pathology)
- Disease Models, Animal
- Electroencephalography
- Hypercapnia
(blood, complications, pathology)
- Hypoxia
(blood, complications, pathology)
- Male
- Prosencephalon
(blood supply)
- Random Allocation
- Rats
- Rats, Wistar
- Specific Gravity
|