Abstract |
In an attempt to improve the selection of patients with neurogenic bladder dysfunction likely to benefit from phenoxybenzamine therapy, the effect of intravenous phentolamine ( Regitine) on the urinary flow rate was determined in normal and abnormal subjects. A nomogram relating mean flow rate to volume voided was constructed to aid in the interpretation of results. In 16 patients with neurogenic bladder dysfunction it was found that a response of more than 0.8 nomogram units indicates a likelihood of clinical improvement with phenoxybenzamine therapy. The clinical applications of this test are discussed.
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Authors | C A Olsson, M B Siroky, R J Krane |
Journal | The Journal of urology
(J Urol)
Vol. 117
Issue 4
Pg. 481-5
(Apr 1977)
ISSN: 0022-5347 [Print] United States |
PMID | 850322
(Publication Type: Journal Article)
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Chemical References |
- Phenoxybenzamine
- Phentolamine
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Topics |
- Adult
- Evaluation Studies as Topic
- Humans
- Male
- Phenoxybenzamine
(therapeutic use)
- Phentolamine
- Prostatitis
(physiopathology)
- Urinary Bladder, Neurogenic
(drug therapy, physiopathology)
- Urination
(drug effects)
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