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Antidiabetic effects of a glycoside of leucopelargonidin isolated from Ficus bengalensis Linn.

Abstract
Glycoside of leucopelargonidin isolated from the bark of F. bengalensis demonstrated significant hypoglycemic, hypolipidemic and serum insulin raising effects in moderately diabetic rats with close similarities to the effects of a minimal dose of glibenclamide. The main difference observed in their effects was that the former significantly enhanced the fecal excretion of sterols and bile acids while the later has no such action even though both controlled hypercholesteremia.
AuthorsS Cherian, K T Augusti
JournalIndian journal of experimental biology (Indian J Exp Biol) Vol. 31 Issue 1 Pg. 26-9 (Jan 1993) ISSN: 0019-5189 [Print] India
PMID8500813 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Anthocyanins
  • Flavonoids
  • Hypoglycemic Agents
  • pelargonidin
Topics
  • Animals
  • Anthocyanins
  • Diabetes Mellitus, Experimental (drug therapy, metabolism)
  • Flavonoids (chemistry, pharmacology)
  • Glycosylation
  • Hypoglycemic Agents (pharmacology)
  • Male
  • Plants, Medicinal
  • Rats
  • Rats, Sprague-Dawley

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