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The use of intravenous ketorolac for the treatment of renal colic in the emergency department.

Abstract
The objective of this study was to report the authors' experience using intravenous ketorolac (Syntex Laboratories, Palo Alto, CA) as an analgesic in the treatment of renal colic in a convenience sample at three suburban community hospital emergency departments. Twenty-five patients with renal colic were participants. Pregnant women, patients with a history of renal or hepatic impairment, bleeding diathesis, active peptic ulcer disease, or hypersensitivity to aspirin or nonsteroidal antiinflammatory drugs (NSAID) were excluded. Ketorolac 30 mg administered intravenously during a 1-minute period, and the following parameters were monitored at times 0, 5, 10, 20, 30, and 60 minutes: pain on a scale of 0 to 10, pulse rate, blood pressure, and adverse side effects. A total of 25 patients were included in our series. Initially, they had a median pain score of 9 with an interquartile range of 1. Thereafter, the median pain scores and (interquartile ranges) were 8 (three) at 5 minutes, 5 (four) at 10 minutes, 2 (four) at 20 minutes, 1 (three) at 30 minutes, and 0 (one) at 60 minutes. There were no adverse side effects observed in any patients. Therefore, it can be concluded that intravenous ketorolac is an effective analgesic agent for the control of pain in patients with renal colic.
AuthorsL S Larsen, A Miller, J R Allegra
JournalThe American journal of emergency medicine (Am J Emerg Med) Vol. 11 Issue 3 Pg. 197-9 (May 1993) ISSN: 0735-6757 [Print] United States
PMID8489656 (Publication Type: Journal Article)
Chemical References
  • Analgesics
  • Tolmetin
  • Ketorolac
Topics
  • Adult
  • Analgesics (administration & dosage, therapeutic use)
  • Colic (drug therapy)
  • Emergencies
  • Humans
  • Injections, Intravenous
  • Ketorolac
  • Kidney Diseases (drug therapy, physiopathology)
  • Male
  • Middle Aged
  • Pain Measurement
  • Tolmetin (administration & dosage, analogs & derivatives, therapeutic use)
  • Treatment Outcome

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