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[Pleural washing with povidone-iodine for treatment of empyema].

Abstract
In this paper, we report two successful cases of empyema treated by pleural washing with povidone-iodine solution. In these two cases, empyema was caused by secondary infection of multi-drug resistant Pseudomonas aeruginosa. First, we replaced intrathoracic drainage tube and washed intrathoracic space with 500-1000 ml saline containing antibiotics (tobramycin, aztreonam) every 8 hours for 10-14 days. But, cultural studies of pleural effusion were positive even after this treatment. So, we tried pleural washing with warm povidone-iodine solution 1:20 diluted with saline every 8 hours. Surprisingly, after 3 days treatment, cultural studies of the pleural effusion became negative. This pleural washing method with povidone-iodine was very effective for treatment of empyema patients.
AuthorsK Takayama, M Hirata, S Nabeshima, A Nabeshima, H Hara, S Kashiwagi
JournalKansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases (Kansenshogaku Zasshi) Vol. 67 Issue 3 Pg. 218-22 (Mar 1993) ISSN: 0387-5911 [Print] Japan
PMID8486978 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Povidone-Iodine
Topics
  • Aged
  • Empyema, Pleural (microbiology, therapy)
  • Humans
  • Male
  • Middle Aged
  • Povidone-Iodine (therapeutic use)
  • Pseudomonas Infections (therapy)
  • Superinfection (therapy)
  • Therapeutic Irrigation (methods)

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