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Blastomycosis in transplant recipients: report of a case and review.

Abstract
Fungi cause serious, often fatal infections in immunocompromised hosts. Recipients of solid organ and bone marrow transplants are predisposed to invasive fungal infections with Candida species, Aspergillus species, and Cryptococcus neoformans. In contrast, infections with Blastomyces dermatitidis have rarely been diagnosed in transplant recipients. We describe a patient who received an orthotopic heart transplant and developed recurrent disseminated blastomycosis. Other reported cases of blastomycosis in transplant recipients are summarized. Clinical presentation, treatment options, and morbidity associated with infections with B. dermatitidis in transplant patients are reviewed.
AuthorsJ S Serody, M R Mill, F C Detterbeck, D T Harris, M S Cohen
JournalClinical infectious diseases : an official publication of the Infectious Diseases Society of America (Clin Infect Dis) Vol. 16 Issue 1 Pg. 54-8 (Jan 1993) ISSN: 1058-4838 [Print] United States
PMID8448319 (Publication Type: Case Reports, Journal Article, Review)
Chemical References
  • Amphotericin B
Topics
  • Amphotericin B (therapeutic use)
  • Blastomycosis (drug therapy, etiology)
  • Female
  • Heart Transplantation (adverse effects)
  • Humans
  • Middle Aged

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