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[Superselective bronchial arterial infusion therapy with cisplatin and epirubicin hydrochloride, mitomycin C-iohexol-Lipiodol emulsion (EMILE) for hilar lung adenocarcinoma: preliminary clinical experience].

Abstract
A case of hilar lung adenocarcinoma was treated by superselective bronchial arterial infusion therapy with cisplatin and epirubicin hydrochloride, mitomycin C-iohexol-Lipiodol emulsion (EMILE) using Tracker -18 infusion catheter. The tumor size was reduced on follow-up CT scans. However, EMILE was also distributed to nontumorous lung tissues around the tumor, and a shrinkage of the right upper lobe and elevations of the right hilus and diaphragm followed. No major complaints and clinical complications during and after the treatment occurred. This therapy was safe and effective for local tumor reduction in a case of hilar lung adenocarcinoma.
AuthorsM Kanematsu, Y Yamawaki, E Matsui, R Mochizuki, H Goto, S Asada, T Imaeda, M Shibayama, H Doi
JournalNihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica (Nihon Igaku Hoshasen Gakkai Zasshi) Vol. 53 Issue 9 Pg. 1073-5 (Sep 25 1993) ISSN: 0048-0428 [Print] Japan
PMID8414933 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Mitomycins
  • Epirubicin
  • Iohexol
  • Iodized Oil
  • Cisplatin
Topics
  • Adenocarcinoma (drug therapy)
  • Aged
  • Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
  • Bronchial Arteries
  • Cisplatin (administration & dosage)
  • Epirubicin (administration & dosage)
  • Humans
  • Infusions, Intra-Arterial
  • Iodized Oil (administration & dosage)
  • Iohexol (administration & dosage)
  • Lung Neoplasms (drug therapy)
  • Male
  • Mitomycins (administration & dosage)

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