Abstract |
This paper describes a matched case-control study to determine the efficacy of BCG vaccine in preventing the occurrence of leprosy in southern Malaŵi, a previously unstudied area. The BCG immunization rate amongst 145 individuals with leprosy was 44.8%, compared to 62.5% in 290 matched controls. The protective efficacy of BCG vaccine against leprosy in this region was estimated to be 63.6%; smallpox immunization had no effect. These findings support the view that BCG vaccine should be considered as a control measure in areas where leprosy is endemic.
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Authors | D M Baker, J S Nguyen-Van-Tam, S J Smith |
Journal | Epidemiology and infection
(Epidemiol Infect)
Vol. 111
Issue 1
Pg. 21-5
(Aug 1993)
ISSN: 0950-2688 [Print] England |
PMID | 8348929
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Adolescent
- Adult
- BCG Vaccine
- Case-Control Studies
- Female
- Humans
- Leprosy
(prevention & control)
- Malawi
(epidemiology)
- Male
- Odds Ratio
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