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Epidermolysis bullosa acquisita: efficacy of high-dose intravenous immunoglobulins.

Abstract
A 16-year-old boy had a 6-year history of a generalized bullous eruption that was resistant to multiple therapies. Findings of immunofluorescent split-skin studies and electron microscopy were consistent with a diagnosis of epidermolysis bullosa acquisita. Treatment with cyclosporine and prednisolone decreased new blister formation. Additional therapy with high-dose intravenous immunoglobulins was successful in controlling the patient's disease.
AuthorsF Meier, K Sönnichsen, G Schaumburg-Lever, R Dopfer, G Rassner
JournalJournal of the American Academy of Dermatology (J Am Acad Dermatol) Vol. 29 Issue 2 Pt 2 Pg. 334-7 (Aug 1993) ISSN: 0190-9622 [Print] United States
PMID8340508 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Immunoglobulin G
  • Immunoglobulins, Intravenous
  • Cyclosporine
  • Prednisolone
Topics
  • Adolescent
  • Chronic Disease
  • Cyclosporine (therapeutic use)
  • Drug Therapy, Combination
  • Epidermolysis Bullosa Acquisita (diagnosis, therapy)
  • Humans
  • Immunoglobulin G (therapeutic use)
  • Immunoglobulins, Intravenous (therapeutic use)
  • Male
  • Prednisolone (therapeutic use)

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