Abstract |
The concentrations of antipyrine in plasma and saliva were equivalent in normal volunteers and in patients with acute viral hepatitis following oral doses of antipyrine. Estimates of clearance, volume of distribution, and half-life made from either plasma or saliva samples were not statistically different in these subjects. Differences in the disposition kinetics of anticted using either plasma or saliva samples.
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Authors | P J Meffin, R L Williams, T F Blaschke, M Rowland |
Journal | Journal of pharmaceutical sciences
(J Pharm Sci)
Vol. 66
Issue 1
Pg. 135-7
(Jan 1977)
ISSN: 0022-3549 [Print] United States |
PMID | 833730
(Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
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Chemical References |
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Topics |
- Acute Disease
- Antipyrine
(blood, metabolism)
- Hepatitis, Viral, Human
(metabolism)
- Humans
- Kinetics
- Male
- Saliva
(metabolism)
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