[The first trial of azinox treatment in a clonorchiasis focus in the Socialist Republic of Vietnam].

Abstract

Trials of biltricide (Merck, India) and azinox, its analog manufactured in this country, carried out in a mixed focus of clonorchiasis and intestinal nematodiases in Vietnam, have not shown any noticeable difference in the efficacy and tolerance of these drugs, that were administered for 3 days in total doses of 60 and 75 mg/kg. The mean efficacy of clonorchiasis therapy was 59.2%, and the invasion intensity reduced by more than 98%. Slight side effects were observed in 86.7% of patients.

• Authors: T L Kieu, A M Bronshteĭn, T P Sabgaĭda
• Journal: Meditsinskaia parazitologiia i parazitarnye bolezni (Med Parazitol (Mosk)) 1993 Jan-Feb Issue 1 Pg. 45-7 ISSN: 0025-8326 [Print] Russia (Federation)
• Vernacular Title: Pervyĭ opyt lecheniia azinoksom v ochage klonorkhoza v SRV.
• PMID: 8336654 (Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article)

Chemical References

• azinox
• Praziquantel

Topics

• Adolescent
• Adult
• Aged
• Clonorchiasis (drug therapy)
• Disease Reservoirs
• Female
• Humans
• Male
• Middle Aged
• Praziquantel (adverse effects, analogs & derivatives, therapeutic use)
• Time Factors
• Vietnam